Dr. Joshua Rosenblat is a staff psychiatrist and clinician-researcher at the Mood Disorders Psychopharmacology Unit (MDPU; within the Poul Hansen Family Centre for Depression) at Toronto Western Hospital. He is also the Medical Director of the Canadian Rapid Treatment Centre of Excellence (CRCTE), Chief Medical & Scientific Officer of Braxia Scientific and co-founder of 1907 Research. Dr. Rosenblat completed his Bachelors of Science at the University of Toronto with a double major in Human Biology and Molecular Biology, minoring in Physiology and Chemistry. He then completed his medical degree at the Schulich School of Medicine at the University of Western Ontario (UWO). He returned to Toronto to complete his residency training in the Department of Psychiatry where he also served as the Chief Resident of the Clinician-Scientist Program (CSP). Throughout medical school and residency, he conducted clinical research on novel pharmacological interventions for mood disorders. He then completed his graduate training in the Department of Pharmacology & Toxicology, studying the effects of ketamine for depression.
Dr. Rosenblat’s clinical focus is treatment-resistant unipolar and bipolar depression, with specialized expertise in pharmacological treatments of mood disorders. His research focus is conducting clinical trials to identify and evaluate novel psychopharmacological interventions for mood disorders that may substantially improve patient outcomes. Current novel targets of interest include the glutamate system, inflammation and the insulin pathway. He is also interested in targeting specific symptom domains, such as suicidality, cognition, anhedonia and mixed features, that do not respond as well to currently available treatment. Specific research programs currently underway include clinical trials evaluating ketamine, pentoxifylline and psilocybin assisted therapy for bipolar and unipolar depression.
Dr. Rosenblat is also actively involved in teaching medical students and residents, with a focus on improving assessment and management skills using a biopsychosocial approach in every patient encounter. His clinical, research and educational interests converge in studying ways to effectively translate research findings into improved patient outcomes through implementation of evidence-based practices in both primary care and specialized mental health care settings.